Lizzy Caplan and Michael Sheen Starring in Showtime’s ‘Masters of Sex’

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Lizzy Caplan has made many a fan through memorable appearances on premium cable shows, from the hilarious and gone-too-soon Party Down to her V-juice-addicted traveler on True Blood. This fall, she has top billing in one: Masters of Sex, a new Showtime series in which she stars alongside Michael Sheen.

Masters of Sex centers on the lives of William Masters and Virginia Johnson (played by Sheen and Caplan, respectively), two real-life researchers who, for decades, pioneered key research on human sexuality and relationships. Naturally, the first teaser for the show focuses on these questions, with some discussion about key matters, such as faking orgasms. The show will premiere on Showtime on September 29th, 2013, and in the meantime, you can catch the very short, inquiry-packed trailer below.